I find I never have enough hot keys and usually end up reconfiguring some windows when I change from crafter to adventurer.
Would it be possible to have multiple User Interfaces stored and recallable?
You could configure your screen how you like, including hot key settings then save, example /saveui Koragancrafter, and load it or others with /loadui, example /load ui Koraganmage.
You would still have the 10 bar 100 key limit , but could more rapidly switch between activities.