I did a search and didn't find anything about this, so not sure if this has been reported already.
I was in Fiery Rift with my biped yesterday and decided to try a Crimson Damage Crystal of Flame. Well it made it so I did no damage. Ok that's fine, I will just remove the affect. So I did what you would normally do, right click the affect and pick "remove affect". There is no "remove affect". So I had to log out of the game to get the affect removed. This is not very handy.